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A Comparison of Quantum Research, Inc.’s Special
Bovine Colostrum/Whey Extract to Other Colostrum and Whey
Products
When Dr. Stoff
was asked the difference between the Quantum Research extract of bovine
colostrum/whey and other colostrum and whey products, his answer was, "That’s
easy. One works and one doesn’t."
If you ask how
he made that evaluation, he reminds the questioner that he has, for nearly four
years, conducted extensive clinical research on the Quantum extract formulations
and other colostrum products. He knows from actual clinical experience that
regular colostrum may have some value, but has a minimal effect upon any
significant immune response.
Dr. Olsztyn
and Dr. Stoff believe that the Quantum colostrum/whey extracts are elite and in
a class of their own. To be compared to other colostrum and whey products is
inevitable, but much like comparing milk to gold such comparisons are
meaningless. There is simply nothing tangible to compare.
Reviewing
literature of companies that market colostrum or whey products one would get the
impression that their commodity is absolutely the most fantastic immune support
substance that ever existed. In fact, they probably say that somewhere in
self-aggrandizing literature.
The Quantum
Research formulations are not in competition with any colostrum or whey products
as there is very little comparison, other than the Quantum extract has its
origin in cows, as does most regular colostrum.
There is
nothing wrong with the commodity colostrum or whey. Both are a good source of
protein and as Dr. Stoff said, "they are better than nothing". What are the
distinct and important differences between the Quantum Research colostrum/whey
extract formula and other formulas?
Quantum
Research’s formulation of a special extract of colostrum/whey and immune
synergists that includes herbs, and other natural substances. Other colostrum or
whey products are simply a commodity like milk or wheat.
Quantum
Research formualtions have been clinically tested for their effectiveness by
medical doctors before being released to the general public. These clinical
studies are also made available to the public.
Quantum
Research products include a special extract of colostrum/whey that is produced
by a patented pre-calving process of immunological stimulation from an exclusive
herd of clean (antibiotic, hormone, pesticide free) and privately managed herd
of cattle. A proprietary post-calving process of select collection,
ultra-filtration and low heat drying produces a collection of very small
molecules that contain transfer factor and other immunological factors. Less
than 1% of the original colostrum/whey is retained and only specific molecules
are harvested. The same material marketed by other companies as colostrum or
whey is discarded and thrown away through this precise process.
Quantum
Research formulations have been shown in clinical studies to dramatically and
consistently increase natural killer (NK) cell activity. Research indicates that
increasing NK cell activity is a tremendous benefit for the restoration and
maintenance of health. No other colostrum and whey products can make the NK cell
function claim based on clinical studies.
The Importance of Natural Killer Cells In Health and
Disease
The clinical
study by Dr. Stoff focused on the ability of the ingredients in Biomune OSF
Plus™ to increase NK cell function. Any statement that natural killer (NK) cells
play an "important role" in human health is as casual as saying that the brain
is important for bodily function. If our brain is not present and active, we
cannot continue "living". If our immune system is not armed and working well, we
will also not continue "living" for very long. NK cell activity is to the immune
system what brain activity is to body.
The immune
system is comprised of millions of cells, numerous chemicals, glands and organs
which all work together via a complex communication system. Immune science uses
terms like "antibodies", "antigens", "B cells", "T cells", "macrophages",
"cytokines", and in the past few years, "natural killer cells". Natural killer
cells have become the focus of much research due to the expanding knowledge of
their value in keeping us healthy.
NK cell
activity and NK cell count are not the same. NK cells may be present in
sufficient numbers, but unless they are activated they are ineffective in doing
their job. Decreased NK cell activity is linked to the development and
progression of many diseases. According to the Center for Disease Control, low
NK cell activity is present in all illness. NK cell function appears to be a
biologic marker for disease and is an important indicator for declining or
improving health.
The following
assertion can be made; if one is suffering from an illness, be it chronic,
recurring or acute, the NK cell activity would be below normal. The restoration
of NK cell activity to a high normal would be desirable, if not necessary, for
recovery. With this in mind, a strategy to accomplish increasing NK cell
activity should accompany both the maintenance of good health and the recovery
from illness.
ABBREVIATIONS: NK; Natural Killer Cell
Low NK cell
activity begins with stress of some type. When the body is unable to adequately
adapt to the environment, there is a resulting compromise of body function.
Stress comes through loss of sleep, overwork, emotional encounters, lack of
exercise, poor nutrition, exposure to toxins, exposure to germs etc.
Acute low NK cell
activity resulting from temporary stress can be eliminated with the elimination
of the stress factor. For example, if we are over-tired and under-nourished, we
can simply rest and eat properly for a few days and recover. However, when we
become continually immune compromised we start developing recurring problems
which may lead to serious or chronic conditions.
Specific intervention
can be necessary to rebuild the immune system in the face of serious or chronic
conditions if recovery is to occur. At a certain point, rest and general
nutrition are just not enough. This is when most people turn to pharmaceutical
products for recovery and symptomatic relief. Unfortunately, this has not been a
viable approach, as drugs do not address the deficiencies that are necessary for
real and lasting recovery. Drugs do not build up the immune system and often
produce a weakening in the long run. The lack of results and the many side
effects of drugs have caused millions to turn to alternative approaches for
their health recovery.
There are numerous
nutritional substances that support the immune system when taken in sufficient
quantities and combinations. Vitamin A, vitamin C and vitamin E, zinc, calcium,
goldenseal and echinacea, are just a few of the vitamins minerals and herbs that
support the immune system. Vitamin C and vitamin E will increase NK cell
activity slightly, but not dramatically nor consistently. In fact, the search
for a safe and effective strategy to enhance NK cell activity and accordingly,
provide effective immune system support has been in progress for several years.
Dr. Stanley R.
Olsztyn, a medical doctor specializing in alternative medicine, has been
developing such products since the 1970’s. He has been working with and
developing special colostrum/whey extracts in combination with herbs, vitamins
and other nutritionals. Dr. Olsztyn discovered that colostrum/whey extracts with
synergistic nutritional components did, in fact, increase NK cell activity both
dramatically and consistently. This explained why the thousands of patients to
whom he had given his formulas responded so well and so quickly. In 1993, after
15 years of clinical research and development, he introduced his results to the
general public.
Concurrently, Dr.
Jesse A. Stoff, a prominent viro-immunologist and researcher, was exploring ways
to expand his protocol for immune system support. He conducted extensive
laboratory evaluation on his patients in his Tucson clinic and was searching for
a "transfer factor" substance that he reasoned would dramatically enhance the
immune system. Dr. Stoff became aware of Dr. Olsztyn’s formulas and began
evaluating them in his practice. As Dr. Stoff deals primarily with severe and
chronic cases, it was a perfect setting to evaluate the Olsztyn products under
the most rigid clinical conditions.
Dr. Stoff published
the results of his findings using Dr. Olsztyn’s special extract of colostrum and
whey in combination with other nutritional factors. The study is most
impressive, showing patient response following dramatic increases in their NK
cell activity. Recovery and remission from many of the most serious of health
problems of this time were documented.
Due to the success of the clinical
studies, Dr. Stoff has joined Dr. Olsztyn for continuing research and the
development of new products using the special colostrum/whey extract and an
array of natural substances. Matol Biomune OSF Plus™ is the first of these new
products.
.
CLINICAL STUDY
THE USE OF DIALYZABLE BOVINE
COLOSTRUM EXTRACT IN CONJUNCTION WITH A HOLISTIC TREATMENT MODEL FOR
NATURAL KILLER CELL STIMULATION IN CHRONIC ILLNESS
|
The following study discusses, summarizes and
demonstrates that properly bovine colostrum and whey extracts used in
combination with the herb Astragalus will help produce significant
increases in Natural killer (NK) cell activity. NK cells are very
important in human health and disease. Defective or absent NK cell
activity is associated with a spectrum of human diseases. Matol Biomune
OSF Plus tm, which combines the herb Astragalus with
such an extract from Quantum Research, Inc. is shown to be a critical
dietary supplement. |
THE USE OF
DIALYZABLE BOVINE COLOSTRUM EXTRACT IN CONJUNCTION WITH A HOLISTIC TREATMENT
MODEL FOR NATURAL KILLER CELL STIMULATION IN CHRONIC ILLNESS By: Jesse A. Stoff, MD, MFHOM, FACLM
Abstract:
A longitudinal
evaluation of the natural killer cell (NK activity) of peripheral blood
lymphocytes was performed in 107 patients with documented and advanced chronic
illness and followed for an average period of 13.2 months. At the time of
primary evaluation and treatment, the absolute value of natural killer cell
activity was significantly lower than the normal range. Hence, the association
of chronic illness with the syndrome of low natural killer cell
activity.
During the follow-up
period, a variety of nutritional agents were given to support natural killer
cell function and then dialyzable bovine colostrum extract was added to the
protocol. In the ensuing months, the curve of NK cell reactivation into normal
ranges and above was monitored as immune system competence was
restored.
The use of natural
immunomodulators including the use of dialyzable bovine colostrum extract can be
concluded as a viable therapeuticum in NK cell reactivation in the face of
chronic illness.
|
Patient outcome
discussion |
 |
| |
|
Patient No.
|
Patient Age
|
Condition |
Month Treated
|
Initial NK Level
|
Last NK Level
|
Comments on Outcome
|
| 144 |
48 |
CFS, Psoriasis |
20 |
21 |
780 |
Back to work, skin improving, high
energy |
| 145 |
50 |
Colon Polyps |
26 |
1 |
174 |
Cured |
| 149 |
48 |
Adenocarcinoma |
22 |
1 |
1030 |
Remission |
| 150 |
77 |
Prostate Cancer |
21 |
7 |
657 |
Remission |
| 151 |
49 |
Hep C |
27 |
3 |
390 |
Remission |
| 152 |
36 |
CFS |
22 |
12 |
380 |
Feeling well and back to
work |
| 153 |
39 |
CFS, EBV, Staph |
27 |
8 |
365 |
Healthy |
| 154 |
62 |
Prostate Cancer |
22 |
3 |
90 |
Remission |
| 155 |
66 |
Carcinoma |
10 |
4 |
830 |
Remission |
| 156 |
57 |
Carcinoma |
11 |
9 |
415 |
Remission |
| 157 |
42 |
Ovarian Cancer |
15 |
23 |
148 |
Remission |
| 158 |
78 |
Prostate Cancer |
3 |
3 |
419 |
Remission |
| 159 |
50 |
AIDS |
36 |
1 |
330 |
Opportunistic infections
ceased |
| 160 |
61 |
CFS |
25 |
0 |
204 |
Feeling good, near
recovery |
| 161 |
62 |
Colon Cancer |
17 |
45 |
466 |
Stabilized |
| 162 |
43 |
Severe Allergies |
30 |
22 |
315 |
Resolved |
| 163 |
56 |
CFS |
23 |
20 |
225 |
Resolved |
| 164 |
44 |
CFS & others |
24 |
1 |
273 |
Resolved |
| 165 |
56 |
CFS |
16 |
26 |
399 |
Resolved |
| 166 |
48 |
CFS |
14 |
4 |
172 |
Resolved |
| 167 |
41 |
Bladder Cancer |
13 |
2 |
148 |
Resolved |
| 168 |
76 |
Prostate Cancer |
19 |
3 |
92 |
Remission |
| 169 |
50 |
HSV-II |
18 |
6 |
282 |
Remission |
| 170 |
47 |
CFS, Colon Polyps |
20 |
3 |
189 |
Much improved |
| 171 |
49 |
CFS |
23 |
1 |
266 |
Steadily improving |
| 172 |
46 |
Ductal Carcinoma |
13 |
11 |
179 |
Remission |
| 173 |
60 |
CMV |
38 |
4 |
297 |
Cured |
| 174 |
72 |
Lymphocytic Leukemia |
24 |
1 |
89 |
Stabilized &
improved |
| 175 |
36 |
CFIDS, HHV-6 |
59 |
18 |
315 |
Resolved |
| 176 |
37 |
Autoimmune Dysfunction |
29 |
1 |
623 |
Normal |
| 177 |
41 |
Myelodysplasia |
9 |
8 |
349 |
Normalized |
| 178 |
82 |
Lymphoma (Non Hodgkin) |
16 |
26 |
634 |
Stable &
progressing |
| 179 |
58 |
Lymphocytic Leukemia |
39 |
0 |
730 |
Stable & dormant |
| 180 |
38 |
Chronic Infection |
31 |
4 |
368 |
Normalized |
| 181 |
36 |
Colitis, Allergy |
36 |
38 |
550 |
Normalized |
| 182 |
55 |
B-cell Leukemia |
14 |
5 |
210 |
Stable & improving |
| 183 |
66 |
Colitis |
16 |
17 |
125 |
Much improved |
| 184 |
65 |
Prostate Cancer |
13 |
21 |
367 |
Stable, good prognosis |
| 185 |
33 |
EBV |
29 |
1 |
295 |
Full remission |
| 186 |
41 |
Thyroditis |
20 |
2 |
230 |
Much improved &
improving |
| 187 |
53 |
CFS |
17 |
16 |
345 |
Improving rapidly |
| 188 |
53 |
Myelodysplasia |
10 |
5 |
249 |
Improving rapidly |
| 189 |
64 |
Prostate Cancer |
19 |
14 |
845 |
Asymptomatic |
| 190 |
65 |
CFIDS, Allergies |
23 |
14 |
398 |
Back to work |
| 191 |
30 |
Basal Cell Carcinoma |
29 |
51 |
140 |
Resolved &
remission |
| 192 |
53 |
Breast Cancer |
22 |
105 |
845 |
Disease free |
| 193 |
76 |
Lung Cancer |
9 |
25 |
88 |
Stabilized &
resolving |
| 194 |
55 |
Colon Cancer |
12 |
40 |
72 |
Obstruction resolved &
asymptomatic |
| 195 |
59 |
CFS |
5 |
11 |
21 |
Returned to active life, feeling
good |
| 196 |
58 |
Breast Cancer |
8 |
11 |
31 |
Recovering well |
| 198 |
65 |
Prostate Cancer |
1 |
2 |
38 |
Full remission |
| 199 |
56 |
CFS |
11 |
20 |
127 |
Energetic & returned to active
life |
| 200 |
62 |
Colon Cancer |
1 |
45 |
219 |
Resolved |
| 201 |
48 |
CFS |
6 |
12 |
101 |
Recovered & "feels like a new
woman" |
| 202 |
47 |
Crevical Cancer |
4 |
1 |
46 |
Cancer, Herpes & Genital Warts in
remission |
| 203 |
49 |
Colon Cancer |
8 |
3 |
49 |
Remission |
| 204 |
51 |
CFS |
19 |
21 |
780 |
Returned to active
life |
| 205 |
36 |
CFS, Lupus |
16 |
7 |
28 |
Remission, back to graduate
school |
| 206 |
40 |
CFS |
13 |
42 |
185 |
Recovered |
| 207 |
48 |
Ovarian Cancer |
12 |
79 |
399 |
Resolved |
| 208 |
40 |
CFS |
13 |
17 |
56 |
Returned to active
life |
| 209 |
43 |
Bladder Cancer |
15 |
2 |
164 |
Remission |
| 210 |
67 |
Prostate Cancer |
2 |
5 |
103 |
Remission |
| 211 |
66 |
Prostate Cancer |
11 |
14 |
608 |
Remission, back to active
life |
| 212 |
50 |
Parotid Cancer |
5 |
29 |
142 |
Remission, back to active
life |
| 213 |
79 |
Prostate Cancer |
20 |
7 |
499 |
Remission |
| 214 |
54 |
Breast Cancer |
9 |
47 |
436 |
Remission |
| 215 |
64 |
CFS |
3 |
0 |
69 |
"Spunky again" |
| 216 |
56 |
CFS |
13 |
2 |
41 |
Full recovery |
| 217 |
49 |
Lupus |
9 |
8 |
38 |
Remission |
| 218 |
63 |
Leukemia |
5 |
117 |
376 |
Improving
significantly |
| 219 |
47 |
Breast Cancer |
5 |
33 |
689 |
Avoided surgery, back to normal
life |
| 220 |
70 |
COPD, CFS |
15 |
1 |
73 |
CFS resolved, back to spry
grandma |
| 221 |
53 |
Breast Cancer,
Thyroiditis |
10 |
132 |
255 |
Thyroid corrected, cancer
remission |
| 222 |
50 |
EBV |
8 |
15 |
28 |
Doing well, feels alive
again |
| 223 |
44 |
Ovarian Cancer |
3 |
23 |
70 |
Remission |
| 224 |
39 |
EBV, Lupus |
7 |
19 |
66 |
EBV remission, Lupus has
disappeared |
| 225 |
52 |
Prostate Cancer |
2 |
5 |
39 |
Full remission |
| 226 |
84 |
Lymphoma |
4 |
26 |
69 |
Full recovery |
| 227 |
49 |
Appendix Adenocarcinoma |
10 |
18 |
56 |
Full remission |
| 228 |
50 |
CFS |
3 |
4 |
44 |
Feeling great again |
| 229 |
77 |
Cancer |
8 |
82 |
348 |
Remission |
| 230 |
55 |
CFS |
5 |
18 |
50 |
Resolved, returned to
career |
| 231 |
21 |
EBV, Severe Herpes
Stomatitis |
14 |
5 |
32 |
Resolved |
| 232 |
49 |
Leukemia |
0 |
2 |
11 |
Remission |
| 233 |
57 |
CFS |
8 |
13 |
40 |
Really well, full
remission |
| 234 |
52 |
CFS |
5 |
2 |
22 |
Improving steadily |
| 235 |
66 |
Renal Carcinoma |
7 |
3 |
11 |
Remission |
| 236 |
55 |
Lupus |
13 |
1 |
15 |
Recovering well, slowly
resolving |
| 237 |
78 |
Prostate Cancer |
6 |
3 |
19 |
Heavy chemo slowed healing, now in
remission |
| 238 |
40 |
CFS |
15 |
100 |
169 |
Full recovery |
| 239 |
48 |
Breast Cancer |
4 |
3 |
38 |
Remission |
| 240 |
31 |
CFS |
1 |
12 |
86 |
Full remission |
| 241 |
65 |
Prostate Cancer |
1 |
18 |
287 |
Full remission |
| 242 |
17 |
Acute Mono |
2 |
0 |
79 |
Full recovery very
fast |
| 243 |
46 |
Ovarian Cancer |
1 |
15 |
118 |
Full remission |
| 244 |
38 |
Breast Cancer |
2 |
3 |
218 |
No sign of disease |
| 245 |
53 |
Lung Cancer |
2 |
9 |
198 |
Improving
significantly |
| 246 |
68 |
Colon Cancer |
2 |
36 |
246 |
Fully recovered |
| 247 |
47 |
Cervical Cancer |
2 |
20 |
182 |
Remission |
| 248 |
31 |
CFS |
2 |
7 |
68 |
Remission in 4 months |
| 249 |
29 |
CFS |
2 |
14 |
92 |
After 8 years illness, 4 months 90% of
old self |
| 250 |
62 |
Lymphoma |
1 |
27 |
68 |
Tumor decreasing |
| 251 |
73 |
Myeloma |
2 |
4 |
148 |
Fully recovered |
| 252 |
26 |
CFS |
2 |
30 |
87 |
Full remission |
| 253 |
43 |
Breast Cancer |
1 |
17 |
289 |
Improving very nicely |
| 254 |
58 |
Myelofibrosis |
2 |
1 |
79 |
Making great
progress | |
Clinical Study
Summary and Discussion The
participants:
Charts of 107
patients who presented with chronic illness which were known to include low NK
cell function were studied to determine their NK cell function response after
being treated with a complimentary medical regimen of therapy. This regimen
included the use of dialyzable bovine colostrum/whey extracts as well as other
elements of the Holistic Medical Paradigm.
The patients
all self-selected this medical approach and most came with specific
expectations, having read (1) Chronic Fatigue Syndrome: The Hidden Epidemic or,
(2) The Definitive Guide to Cancer Therapy.
An overview of the
immune system:
The marvelous array
of deftly interacting cells that defend our body against invaders, arise from a
few precursor cells that first appear at about 9 weeks after conception. From
that point on, the cells of the immune system go through a continuously repeated
cycle of growth and development and become fully competent at around 6 months of
age after our birth.
The parent cells of
our immune system are referred to as stem cells. These are the cells upon which
the immune system depends to both reproduce itself and gives rise to the many
specialized lineage's that spring from it; the B cells, macrophages, natural
killer (NK) cells, helper T cells, etc.
The cells of the
immune system are not isolated in a single body space or arranged in the form of
a single organ. Instead, the majority of them exist as potentially mobile
entities unattached to other cells. This characteristic is crucial to their
function. Every minute of every day, war is waged within our body. The
combatants are too small to see. Some, like the infamous HIV virus, are so small
that 230 million would fit on the period at the end of this sentence. Yet, they
employ tactics that can vanquish the much larger cells upon which our immune
system is based. Usually, we never even notice the battles within us.
We have evolved
legions of defenders, specialized cells that silently destroy the unseen enemy.
Sometimes these warriors mistake harmless invaders such as pollen for deadly
foes and trigger an allergic response. Occasionally, some of our own cells begin
the mutinous uncontrolled proliferation characteristic of cancer and manage to
evade the surveillance of our body's defensive forces. For every successful
penetration of our defenses, millions of attempts are repelled. We sleep
securely at night trusting the invisible vigilantes of our immune
system.
The science and
practice of immunology traces back to 1721 to Lady Mary Wortley Montagu. She
introduced England to a Turkish process of inoculation with unmodified smallpox
virus in an attempt to stem the ravages of the normal course of the disease. Her
techniques were quite crude and as many as her patients died as survived but
those that survived were immune to the disease forever more.
Over the decades and
centuries, scores of doctors and researchers honed the art of immunology into a
more and more refined science. Many of the wonderful blood tests that we have
today and information that we now know about immunology was unknown to us a
scant 20 years ago. Information on the science of immunology doubles at the rate
of approximately every 5 to 6 years. So, we must remember that the wonderful
ways that we have today to support and direct the immune system to help protect
us and fight off illnesses is a mere foreshadow of things to come in the (near)
future
Our immune system is
a miracle of evolution. There is interesting research to suggest that elements
of our immune system were, at one time, actually independent organisms. They
were incorporated into our body, millions and millions of years ago, as a type
of symbiotic mutually beneficial relationship. Our immune system is not
controlled by any central organ such as the relationship of our brain to our
nervous system. Rather, it has developed and functions as a kind of biological
democracy where the individual members achieve their ends through an information
network of biochemical substances called, "cytokines".
Many different
variables in our environment and lifestyle can effect the efficiency of its
function. Our immune system accounts for approximately 1% of our body's 100
trillion cells. These defender cells originally arise in our bone marrow and
mature in other parts of our body, the thymus, spleen and lymph glands. The
different lineage's which develop all share one common objective; to identify
and destroy all substances, living or inert, that are recognized as foreign to
our body. This includes cancer cells that challenge our immune system everyday
for each and every one of us.
NK Cells:
NK cells were
discovered in the 1970's and constitute up to 15% of the total lymphocyte
population in normal healthy subjects. They are capable of killing a broad range
of tumor and virus infected cells. Depressed NK cell activity and depressed NK
cell populations are associated with the development and rapid progression of
cancer, hepatitis, AIDS, Chronic Fatigue Syndrome, various immunodeficiency
syndromes, and certain autoimmune diseases. In my practice I almost exclusively
work with people with severe and chronic diseases, that are known to present
abnormally low levels of NK cell function.
NK cells now appear
to present the first line of defense against metastatic spread of tumors. In
numerous studies, low NK cell populations were correlated with greater and more
rapid spread of tumors with shorter host longevity and with greater
morbidity.
The immune
response:
There are four
critical phases to the immunological response and lifestyle issues and some
dietary supplements can influence them.
During phase
one, the offending invader is identified and recognized as being foreign to
our body and then quickly consumed by hungry roving macrophages. You can think
of macrophages as little PAC men that are found in all of the tissues in our
body and circulating around in our blood stream looking for their next free
lunch. They seize upon this foreign agent, engulf it, eat it and release a
series of cytokines that then trigger the 2nd phase of the immunological
reaction.
In phase
two, these biochemical substances then activate the helper T cells that have
the job of coordinating the counterattack on a body-wide scale. The T cells then
begin to multiply and release other cytokines that further stimulate more T
cells, B cells, and natural killer cells. As the number of B cells increase, the
helper T cells signal them to begin producing antibodies, thus, bringing us to
the 3rd stage of the immunological response.
In the
third stage, the antibodies are circulating around in our blood stream
and are attaching to the foreign virus or bacteria causing them to be more
quickly engulfed by macrophages or killed by natural killer cells.
The fourth
stage of the immunological response begins when the circulating antibodies
no longer have a target and the suppresser T cells call a truce to the
immunological reaction bringing about a new balance, or homeostasis, in our
system. Special cells of the immune system remember what had transpired so that
if again attacked by the same organism, our body could respond much faster.
These cells also release special little molecules called, "transfer factor" to
help keep the pump primed, so to speak.
Thus, what may
have been a 10-day bout from our first exposure to that particular virus, in the
future may be a cold that lasts no more than 24-72 hours.
Immune-modulation:
Immune-modulation is
a new and key step in supporting immune function. This can include a number of
different substances, depending upon the situation, including: transfer factor
(obtained in specially prepared colostrum/whey extracts), Astragalus,
Arabinogalactan, Viscum extracts, vitamin C, iodine, lactoferrin, certain amino
acids, neurotransmitter hormones and the prohormone DHEA.
Transfer
Factor:
In the study group,
generic NK cell response was monitored using transfer factor, obtained in
specially prepared colostrum/whey extracts, along with the herb Astragalus that
is known to accelerate and support immunological reactions. The transfer factor
component was produced from cows that have been immunologically stimulated using
a patented process. This process does not hurt the cow. In fact, it stimulates
the cow’s immune system for its own protection.
When a cow gives
birth to a calf, the first flow of milk is called the colostrum. The colostrum
is collected and the transfer factor molecules are extracted. At appropriate
opportunities, collection can also occur from the milk following colostrum. This
is generally referred to as whey. Since none of the milk proteins remain, these
products are safe even for people with a dairy allergy. The purified transfer
factor can then be given to people to passively stimulate their NK cells
function to alert-activity status, thus protecting them to a significant degree
from illness as well as helping them recover from illness.
Lifestyle:
Lifestyle issues that
will affect the functioning of our immune system include exposure to toxins
(heavy metals, petrochemicals, radiation, etc.) and dietary and nutritional
deficiencies that can rob the immune system of the biochemical foundation that
it relies upon in order to function normally. Another major lifestyle issue
relative to immune function is stress.
Dietary
Supplements used by the Study Group:
The use of other
nutritional support factors in conjunction with the dialyzable colostrum/whey
extract and astragalus was important for patient recovery. However, I want to
point out three significant factors in relation to that fact:
Most of the patients
were advanced in their conditions and had tried other approaches for their
health recovery before I saw them in my clinic.
The dialyzable
colostrum/whey extract was critical to their recovery. Without that component,
providing the transfer factors discussed herein, many of the patients simply
would not have recovered.
I have utilized a
wide array of well-known and privately prepared colostrum products with
disappointing results. These products were not helpful to my patients as they
failed to significantly increase NK cell function or consistently provide any
other significant immunological benefits that could be measured.
I also observed that
people who were not severely compromised responded well to daily supplementation
of the colostrum/whey extract and astragalus without additional nutritional
supplementation. Even though adequate nutritional support is important it was
noted that the extract of dialyzable colostrum/whey and astragalus is very
powerful and valuable in combination without additional
supplementation.
The importance of
prevention:
With any health
problem, it is much more prudent and efficient to prevent disease by maintaining
a high level of immune function. Research has shown that low NK cell activity is
present nearly all illness. A daily dietary regimen that includes dialyzable
bovine colostrum/whey extract has been shown to significantly help maintain high
NK cell activity and thereby dramatically increase the ability of the immune
system to maintain a healthy condition.
Conclusions:
This Study Group
demonstrates that stimulation of NK activity paralleled restored resistance to
illness and recovery from illness. NK cell activity is correlated with disease
status in those patients with hematologic malignancy such as leukemia and
lymphomas as well. In some studies, on patients with leukemia, a sudden and
maintained decrease in NK cell activity was reported nearly always to proceed
relapse, even if the patient had been in complete remission for some time. This
also correlated with a general drop in the percentage of lymphocytes as measured
in a standard blood test. NK cell function is a well-regulated activity subject
to both inhibitory and excitatory control.
REFERENCES
1. "Purification of
transfer factors", Rosso, S.J. et al, Mol. Immunol. 1992, Feb; 29(2): 167-82
2. Transfer factor is
effective across different mammalian species. "Isolation and purification of HSV-1
specific transfer factor produced by HSV-1 immunized goat leukocyte dialysate" by
Dr. Qitly et al, Acta Virol 1992, May; 36(3): 231-8
3. Transfer factor is
just as effective when taken orally as by injection. "Murine transfer factors: dose-response
relationships and routes of administration" Kirk Patrick, C.H., et al,
Cell Immunol, 1995, Sep; 164(2): 203-6
4. "Transfer factor
presents relapse in herpes keratitis patients; a pilot study" Pizza, G. et al, Biotherapy 1994; 8(1): 63-8
5. "Adjuvant
treatment using transfer factor for bronchogenic carcinoma: long- term follow-up", Whyte, R.I. et al, Arr
Thoracic Surgery, 1992, Mar; 53(3): 391-6
6. "Immunotherapy
with transfer factor of recurrent herpes simplex type I", Estranda-Parra, S. et al, Arch Med Res,
1995;26
7. "Effect of
Brucella abortus transfer factor in preventing murine brucellosis", Stevens, M.G. et al, Immunol Med Microbiol,
1995, Jul; 11(4): 279-84
8. "Transfer factor
in malignancy", Pizza, G. et al, Prog Drug Res 1994; 42: 401-21
9. "Specific transfer
factor with activity against Epstein-Barr virus reduces late relapse in endemic Burkitt’s lymphoma",
Neequaye, J. et al, Anticancer Research 1990 Sept-Oct; 10 (5A):
1183-7
10. "A controlled
trial of bovine dialyzable lukocyte extract (transfer factor)
for cryptosporidiosis in
patients with AIDS" McMeeking, A. et al, J. Infect Dis, 1990 Jan; 161(1): 108-12
11. Clark D, Wyatt K:
Colostrum, Life’s First Food. Salt Lake City: CNR Publications, 1996.
12. Lange S: Immune
mechanisms of cardiac disease. New England Journal Of Medicine 330(7): 1129, April 21,
1994.
13. Kohl S, et al:
Human colostral cytotoxicity: antibody-dependent cellular cytotoxicity against herpes simplex infected
cells mediated by colostral cells. Journal of Clinical Laboratory
Immunology 1:221-224.
14. Acosta-Altamirano
G, et al: Anti-amoebic properties of human colostrum. Adv Exp Med Biol 216B: 1347-1352,
1987.
15.
Boesman-Finkelstein M., et al: Passive oral immunization of children.
The Lancet. 49:1336, 1989.
16. Haynes BF, Fauci
AS: Introduction to clinical immunology. Part II, section 2. in: Harrison’s Principles of
Internal Medicine, Eleventh Edition. Braunwald E (eds), et al. New York: McGraw
Hill Book Co, Janusz M, et al:
Immunoregulatory properties of synthetic peptides: fragments of a proline-rich polypeptide from
bovine colostrum. Molecular
Immunology 24(10): 1029-1031, 1987.
17. Kim K, et al: In
vitro and in vivo neutralizing activity of human colostrum and milk against purified toxins A and B of
Clostridium difficile. T Infect Dis 150:57-61, 1985.
18. Ogra P, et al:
Colostrum derived immunity and maternal neonatal interaction. Annals NY Acad Sci 409:82-92,
1983.
19. Palmer EL, et al:
Antiviral activity of colostrum and serum immuno- globulins A and G. J Med Virol 5:123-129,
1980.
20. Sabirl, AB:
Anti-poliomyelitic substance in milk from human beings and certain cows. T Dis Children 80:866-870,
1950.
21. Spik, G., et al.,
Bacteriostasis of a milk-sensitive strain of E. coli by immuno- globulins and iron-binding proteins
associated with colostrum. Immunology 35:663-670, 1981.
22. Stephan W, et al:
Antibodies from colostrum in oral immunotherapy. J Clin Chem Clin Biochem
28:19-23,1990.
23. Wada N, et al:
Neutralizing activity against Clostridium difficile toxins in
the supernatants of cultured
colostral cells. Infect Immune 29:545-550,1980.
24. Ferrer-Argote VE;
Romero-Cabello R; Hernandez-Mendoza L; Arista- Viveros A; and others Successful treatment of severe complicated
measles with non-specific
transfer factor. Department of
Hematology, Hospital General de Mexico, DF, Mexico. In Vivo 1994 Jul-Aug; 8 (4):
555-7
25. Rebulla P;
Tedesco F; Radillo O; Battaglioli M; and others Inhibition of in vitro adherence of
antibody-coated red cells to
monocytes by the dialyzable leukocyte extract. Centro Trasfusionale e di Immunologia dei
Trapianti, Ospedale Policlinico, Milan, Italy. Transfusion 1991 Mar-Apr; 31 (3):
218-21
26. Fazio M; Negri L;
Calabrese F; Correggia F; and others A new method for the in vitro transfer of
delayed hypersensitivity by
dialysed transfer factor. J
Nucl Med Allied Sci 1990 Oct-Dec; 34 (4 Suppl): 271-4
27. Fazio M;
Calabrese F; Giacomasso S; Meina G; and other Transfer in vivo of tuberculin
hypersensitivity by sensitized lymphocytes. Chair of Medical Oncology, University of
Turin, Italy. Panminerva Med
1993 Sep; 35(3): 149-53
28. Mrazova A; Mraz
J Transfer factor and its
signification for practice. Sb
Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove 1993; 36(3): 117-37
29. Sumiyama K;
Kobayashi M; Miyashiro E; Koike M Combination therapy with transfer factor and
high dose stronger neo-minophagen C in chronic hepatitis B in
children (HBe Ag positive). Department of Pediatrics, Wakayama Medical
College, Japan. Acta Paediatr
Jpn 1991 Jun; 33(3): 327-34
30. Snirc J; Mikula
I; Pistl J The induction of
specific protection against Actinobacillus pleuropneumoniae infection by specific
DLE. Department of Microbiology
and Immunology, University of Veterinary Medicine, Kosice,
Slovakia. Acta Microbiol Hung
1993; 40(4): 325-33
31. Qi HY; Wan ZF; Su
CZ Isolation and purification
of HSV-1 specific transfer factor produced by HSV-1 immunized goat leukocyte
dialysate. Department of
Biochemistry, Fourth Military Medical University, Xian, P.R. China. Acta Virol 1992 May; 36(3): 231-8
32. Fernandez O; Diaz
N; Morales E; Toledo J; and others Effect of transfer factor on
myelosuppression and related morbidity induced by chemotherapy in acute
leukaemias. Hospital
Universitario Dr. Carlos J. Finlay, Marianao, Cuba. Br J Haematol 1993 Jul; 84(3):
423-7
33. Kirkpatrick
CH Structural nature and
functions of transfer factors. Conrad D. Stephenson Laboratory for Research
in Immunology, National Jewish
Center for Immunology and Respiratory Medicine, Denver, Colorado 80206.
REVIEW ARTICLE: 26
REFS. Ann N Y Acad Sci 1993
Jun 23; 685: 362-8
Study Group Profile
Background:
NK cell activity
(Lytic Units) in a healthy
population 150-225
NK cell activity
(Lytic Units) in the U.S.
population 20-50
Study Group size and
gender:
107
participants:
59 females
48 males
Average age:
53 years
Youngest: 17
years
Oldest : 83
years
Presenting disease as
a percentage of the Total Study Group:
Cancer
50%
Chronic Fatigue
Syndrome 30%
Others
20%
Including Lupus, Allergies,
Fibromyalgia, Blood Disorders, Chronic Infections,
Recurrent Infections,
Autoimmune Diseases, and Cervical Dysplasia/Metaplasia.
All Study Group
participants recorded significantly higher NK cell activity.
Average
initial NK cell activity 18 Lytic Units.
Average final
NK cell activity 246 Lytic Units.
Average monthly
increase in NK cell
activity by
participants 28.25 Lytic Units.
Average percentage
of improvement 1,267%.
Treatment
period:
Total participant
treatment time 1,422 months.
Average participant
treatment time 13.2 months.
Number of capsules
used by participants:
2-8 per day.
20.
GRAPHIC ILLUSTRATION OF CLINICAL STUDY
- Average NK Cell activity
in a Healthy Population is 150-225
- Average U.S. Population NK
Cell activity is 20-50
- Study includes over 1400
Treatment months for 107 patients
- Average monthly increase
by patients was 28.25 Lytic Units
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- Participant profile:
Average age 53 ( youngest: 17 - oldest: 84)
- Diseases presented by
study participants
- Cancer - Chronic Fatigue Syndrome -
Lupus - AIDS, HIV - Hepatitis C - Allergies - Colitis
- Chronic Infection
- Low NK Cell count is
associated with a wide spectrum of human illnesses.
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Biomune OSF Plus™
The potential
benefits available through colostrum and whey are being discussed everywhere.
Claims of benefit from the consumption of "Pure, Clean Colostrum" or "Filtered
Whey" are everywhere. Indeed, the benefit of breast-feeding infants has covered
magazine racks for years.
Bovine colostum is
touted as the "new" source of health. Bovine colostrum is now a commodity.
Buyers and sellers from all over the world are being brought together for the
purpose of creating a new marketable commodity. New companies have emerged to
sell this commodity in various forms of "after-market" marketing.
Though bovine
colostrum has some demonstrated benefit, by itself bovine colostrum is not a
silver bullet. It is simply another commodity like wheat or milk. As with all
commodities, all are not created equal and do not contain equal characteristics.
Quantum Research, Inc. and Dr. Jesse Stoff have demonstrated that high quality,
highly controlled extracts can be combined with other nutritional ingredients to
create significant products that can bring changes in the performance of the
immune system.
Quantum Research,
Inc. is able to create the amazing extracts used in the products for several
reasons.
They use a
proprietary technology, protected by a totally unique and protected patented
process.
They utilize a
privately managed dairy herd that originated over thirty years ago.
They access nearly
forty years of experience in bovine colostrum collection and study.
Dr. Stoff and/or Dr.
Olsztyn have used these extracts for over twenty years in medical
practice.
Biomune OSF Plus™ utilizes the herb
astragalus in combination with a special extract of dairy colostrum and whey.
Clinical studies indicate that this combination creates a synergistic effect on
the immune system resulting in elevation of NK cell activity.*
Astragalus The herb Astragalus, with the Latin
name, Astragalus membranaceus, is derived form the root of this perennial
herb which is Chinese in origin and considered a traditional Chinese herb.
Astragalus is considered an immune stimulation herb. The "stem cells" in the
bone marrow are increased and their development is stimulated into active immune
cells that are then released into the body. Essentially, every phase of the
immune system activity is stimulated by Astragalus.
Active ingredients
contained in astragalus include bioflavanoids, choline, and astragalan B, a
polysaccharide. Astragalan B has been shown in animal studies to be effective at
protecting the body against a number of toxins, controlling bacterial infections
and stimulating the immune system. Astragalan B appears to work by allowing the
body’s immune system to attack the outer membranes of viruses, destabilizing
their defenses and allowing them to be overwhelmed by the immune
response.
Astragalus increases
interferon production and enhances NK and T cell function, increasing resistance
to viral conditions. Astragalus has also been shown to support the body in
peripheral vascular disease and peripheral circulation. Astragalus aids adrenal
gland function that often needs support in chronic and degenerative health
states.
Researchers in China
have conducted recent studies which report that Astragalus is an effective
treatment for supporting the immune system in cancer patients. Two separate
studies followed patients receiving traditional chemotherapy and radiation
treatment, which typically devastate the immune system and leave the recipients
weak and susceptible to new opportunistic infections. Patients receiving
astragalus extracts had twice the survival rate of those only receiving standard
therapies. Further studies in the U.S. confirmed that Astragalus has unique
immunity enhancement qualities.
Astragalus has been available China for
centuries and has a long history of use in traditional medicine in China. It is
used to strengthen the Wei Ch’i or "denfensive energy". It is regarded as a
tonic for stimulating the immune system and increasing energy levels. It has
also been used as a diuretic and a vasodilator for respiratory infections. It
has also been used for colds, flu and to increase stamina.
* These statements have not been
evaluated by the FDA. This product is not intended to treat, diagnose or cure
any diseases.
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Ingredients:
BIOMUNE OSF™
Plus |

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Bovine
colostrum/whey extract (Ai/E10®) |
 |
Astragalus
(root). |
[Order Now]
Recommended
use
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BIOMUNE OSF™
Plus: 1 Capsule a day
® Registered trademark of Quantum research, Inc.
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